{"id":2848,"date":"2020-05-06T12:23:55","date_gmt":"2020-05-06T10:23:55","guid":{"rendered":"https:\/\/www.barcelonaglobal.org\/blog\/?p=2848"},"modified":"2020-12-03T10:37:05","modified_gmt":"2020-12-03T09:37:05","slug":"micro-rinones-para-combatir-a-la-covid-19","status":"publish","type":"post","link":"https:\/\/www.barcelonaglobal.org\/blog\/barcelona-city-of-talent\/micro-rinones-para-combatir-a-la-covid-19\/","title":{"rendered":"Micro ri\u00f1ones para combatir a la Covid-19"},"content":{"rendered":"<p><!-- VideographyWP Plugin Message: Automatic video embedding prevented by plugin options. --><br \/>\n<div class=\"row wpb_row row-fluid\"><div class=\"wpb_column columns medium-12 thb-dark-column small-12\"><div class=\"vc_column-inner  \"><div class=\"wpb_wrapper \">\n\t<div class=\"wpb_text_column wpb_content_element  \" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<div class=\"elementor-element elementor-element-5076d84 elementor-widget elementor-widget-heading\" data-id=\"5076d84\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n<h2 class=\"elementor-widget-container\"><strong>N\u00faria Montserrat, investigadora y Senior Group Leader en el Institut de Bioenginyeria de Catalunya (IBEC)<\/strong><\/h2>\n<\/div>\n<div class=\"elementor-element elementor-element-4d21ddd elementor-widget elementor-widget-spacer\" data-id=\"4d21ddd\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n<div class=\"elementor-widget-container\">\n<div class=\"elementor-spacer\">\n<div class=\"elementor-spacer-inner\"><span style=\"font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, Oxygen-Sans, Ubuntu, Cantarell, 'Helvetica Neue', sans-serif;\">En estos d\u00edas complicados, todos nos encontramos librando una lucha pac\u00edfica desde casa. Pero hay quienes nos defienden desde el frente, trabajando duro desde los hospitales, y tambi\u00e9n desde los laboratorios.<\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"elementor-element elementor-element-3a88dac elementor-widget elementor-widget-text-editor\" data-id=\"3a88dac\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n<div class=\"elementor-widget-container\">\n<div class=\"elementor-text-editor elementor-clearfix\">\n<p class=\"p1\"><span class=\"s1\">Investigadores alrededor del mundo no descansan en su prop\u00f3sito de encontrar un tratamiento y la cura a la Covid-19. En especial, existe un grupo internacional de cient\u00edficos que han identificado un\u00a0f\u00e1rmaco\u00a0que\u00a0bloquea\u00a0el\u00a0virus SARS-CoV-2\u00a0en las primeras fases de la infecci\u00f3n. Y desde Barcelona, el equipo de N\u00faria Montserrat, investigadora y Senior Group Leader en el Institut de Bioenginyeria de Catalunya (IBEC), participa aportando sus conocimientos en el campo de la medicina regenerativa.<\/span><\/p>\n<p class=\"p1\"><span class=\"s1\">Natural de Barcelona, N\u00faria lleva a\u00f1os trabajando en la pluripotencia para la regeneraci\u00f3n de \u00f3rganos. En concreto, ella y su equipo desarrollan organoides de ri\u00f1ones, mini \u00f3rganos que simulan de manera muy parecida la arquitectura y la funci\u00f3n de ri\u00f1ones reales, por lo que pueden responder a est\u00edmulos de igual forma que un \u00f3rgano \u2018nativo\u2019. En la actualidad, la medicina de precisi\u00f3n utiliza los organoides para poder hacer testeos de mol\u00e9culas o de f\u00e1rmacos, ya que acorta los tiempos de experimentaci\u00f3n al utilizar c\u00e9lulas a semejanza de las humanas, sin tener que utilizar animales, por ejemplo, y as\u00ed probarlas en pacientes en una fase m\u00e1s avanzada.<\/span><\/p>\n<p class=\"p2\"><span class=\"s1\">Y ese ha sido el papel de Montserrat y de su equipo en este importante descubrimiento: crear miles de estos mini ri\u00f1ones para probar en ellos con \u00e9xito un f\u00e1rmaco experimental, el APN01<\/span><span class=\"s2\">,<\/span><span class=\"s1\">\u00a0inhibidor de la infecci\u00f3n de este nuevo coronavirus. Para entender c\u00f3mo funciona, tenemos que saber que muchos de nuestros \u00f3rganos tienen \u2018puertas de acceso\u2019 que el virus encuentra de forma natural para poder entrar. Por lo tanto, el APN01 act\u00faa como una \u2018puerta falsa\u2019, por donde el virus intenta acceder, pero no puede. Este enga\u00f1o molecular impide que el virus se replique y siga infectando. Se ha comprobado que este f\u00e1rmaco es capaz de reducir hasta 5000 veces la cantidad de virus presente en el tejido y, gracias a esto, se ha autorizado realizar un ensayo cl\u00ednico en hospitales de Alemania, Austria y Dinamarca a 200 enfermos de Covid-19 para ver la reacci\u00f3n de este medicamento en pacientes.<\/span><\/p>\n<p class=\"p2\"><span class=\"s1\">Echando un vistazo al curriculum vitae de la profesora de investigaci\u00f3n ICREA N\u00faria Montserrat, podemos descubrir m\u00e1s de 50 art\u00edculos y muchos otros proyectos, adem\u00e1s de prestigiosos reconocimientos como la beca ERC-Starting en 2014 y la beca Ram\u00f3n y Cajal (primera candidata clasificada, 100\/100 puntos, en 2015). Con sus organoides, en un futuro, se podr\u00edan llegar a crear tejidos o estructuras mayores, equivalentes a trozos de ri\u00f1ones, para que sean trasplantados. Esto es un reto muy ambicioso y a\u00fan tendremos que esperar algunos a\u00f1os para verlo.<\/span><\/p>\n<p class=\"p2\"><span class=\"s1\">La aportaci\u00f3n que esta bi\u00f3loga ha hecho a la medicina en los \u00faltimos d\u00edas, esta teniendo una utilidad inmediata en la lucha contra el coronavirus. Sin lugar a duda, esto es un claro ejemplo de que la fusi\u00f3n entre la ingenier\u00eda, el dise\u00f1o y los estudios de campo de la biolog\u00eda del desarrollo ser\u00e1n\u00a0imprescindibles para la medicina del futuro y hace destacar el papel de Barcelona, como hub de investigaci\u00f3n, y de centros como el IBEC en la ciencia de frontera.<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\t\t<\/div>\n\t<\/div>\n<\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"N\u00faria Montserrat, investigadora y Senior Group Leader en el Institut de Bioenginyeria de Catalunya (IBEC) En estos d\u00edas complicados, todos nos encontramos librando una lucha pac\u00edfica desde casa. Pero hay quienes nos defienden desde el frente, trabajando duro desde los hospitales, y tambi\u00e9n desde los laboratorios. Investigadores alrededor del mundo no descansan en su prop\u00f3sito&hellip;","protected":false},"author":182764262,"featured_media":2879,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[19],"tags":[20,29,133,28,116,127,115],"thb-sponsors":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Micro ri\u00f1ones para combatir a la Covid-19 | Barcelona Global Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.barcelonaglobal.org\/blog\/barcelona-city-of-talent\/micro-rinones-para-combatir-a-la-covid-19\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Micro ri\u00f1ones para combatir a la Covid-19 | 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